Not known Details About https://www.ceesdekker.net

Not known Details About https://www.ceesdekker.net

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‘Yes, that is certainly about right. I seek out a Actual physical knowledge of Organic units within a base-up way. I do think you may distinguish 3 strains of study in my team in the mean time. The main issues chromosome construction: How will you get a metre-lengthy DNA polymer folded and organised in this type of microscopic mobile? Now we have created visualisation tactics that make it possible for us to check how, as an example, SMC proteins loop DNA (movie on Youtube) so that you can build up chromosomes.

Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules

The following articles are merged in Scholar. Their put together citations are counted just for the initial post.

2007, to start with serious-time detection of strand Trade in homologous recombination by RecA; discovery of the very low persistence duration of finishes of microtubules; and solved the mechanism of biosensing with carbon nanotubes

2015, discovery that condensin is a really versatile protein structure; and to start with detection of DNA knots employing nanopores

While in the a long time subsequent these discoveries, my study pursuits shifted to biophysics and nanobiology, And that i turned considerably less associated with the development of nanotube electronics. The main target of numerous researchers in the field also shifted to graphene (where by, funnily plenty of, the primary graphene cees dekker ribbons had been described as ‘nanotubes which have been Minimize open together their size’) right after the discovery of The 2-dimensional materials in 2004.

We shape bacteria into sorts that deviate from their purely natural phenotype. Specially, I'll present our ability to condition Stay E. coli micro organism into novel designs like rectangles, squares, triangles and circles.

2000, discovery that nanotubes can carry remarkable significant present densities; fixed the controversial problem of electronic transportation as a result of DNA molecules by measurements of insulating conduct at The only molecule amount; and demonstration of the AFM method for solitary-molecule manipulation of nanotubes

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At the moment, we also realized that it ought to be probable to employ one semiconducting carbon nanotube for making a transistor — and we established out to really make it. We stretched personal semiconducting nanotubes across metallic electrodes and used the fundamental silicon substrate to be a gate electrode, developing The fundamental three-terminal structure of the area-impact transistor (Fig.

Testing pseudotopological and nontopological types for SMC-pushed DNA loop extrusion against roadblock-traversal experiments

Mother nature Physics thanks the nameless reviewers for their contribution into the peer overview of this do the job.

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It had been an exceptionally fascinating time, for the duration of which I been given lots of assist from Delft College of Technology, in which I used to be a professor at the time, and I started out various collaborations with molecular biologists. That served me discover a whole lot.’